Convenient biological assay for polyethylene glycol-interferons in patients with hepatitis C.

نویسندگان

  • Anne Boulestin
  • Nassim Kamar
  • Florence Legrand-Abravanel
  • Karine Sandres-Saune
  • Laurent Alric
  • Jean-Pierre Vinel
  • Lionel Rostaing
  • Jacques Izopet
چکیده

The vesicular stomatitis virus cytopathic effect reduction assay is suitable to quantify polyethylene glycol-alpha interferon 2a (PEG-IFN-alpha 2a) and PEG-IFN-alpha 2b. Human serum and ribavirin did not interfere with the assay. This bioassay was successfully used for assaying PEG-IFN-alpha 2a and PEG-IFN-alpha 2b in serum samples from patients undergoing combination therapy.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 48 9  شماره 

صفحات  -

تاریخ انتشار 2004