Natriuretic peptide testing for heart failure diagnosis, inpatient management and outpatient cardiac care
نویسنده
چکیده
This article highlights natriuretic peptide synthesis and release. Based on essential clinical trials the article gives medical insights into the use of natriuretic peptides in the emergency setting. The natriuretic peptides help confirm or rule out a diagnosis of heart failure and shorten the visit to the emergency room in addition to reducing the overall cost. However, when interpreting natriuretic peptide results potential confounders also have to be taken into consideration. The confounders include advancing age and therefore age-adjusted cutpoints are often used. Both in the inpatient and the outpatient setting the natriuretic peptides seem to have a potential for optimizing heart failure management. At discharge the natriuretic peptides are prognostic for mortality and/ or readmission and thus give helpful guidance on the appropriate time for discharge. In the outpatient setting the natriuretic-peptide-guided therapy has been shown to give significantly reduced all-cause mortality and heart-failure-related hospitalizations when compared to clinically guided therapy.
منابع مشابه
Evaluation of Brain Natriuretic Peptide plasma levels in children with Congenital Heart Diseases
ObjectiveThis study aimed to assess Brain Natriuretic Peptide in early diagnose of cardiac function in children with Congenital Heart Diseases.MethodologyThis study was performed on children with CHD and healthy. Severity of heart failure modified Ross classification system was used for grouping patients in four classes. For all participants, height, weight and head circumference were measured....
متن کاملClinical and Biochemical Assessments of Circulating B-Type Natriuretic Peptide as a Useful Marker in Pediatric Cardiac Patients
Background Although the left ventricle is the major site of BNP secretion in response to cardiac pressure or volume overload, the myocytes of both atria and ventricles secrete B- type natriuretic peptide (BNP). This study aimed to assess and compare the plasma levels of BNP in common pediatric cardiac diseases to clarify its pathophysiological role and evaluate its po...
متن کاملNational Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Clinical Utilization of Cardiac Biomarker Testing in Heart Failure WRITING GROUP MEMBERS
I. Overview of Heart Failure. . . . . . . . . . . . . . . . . . . . . . .e99 A. Context of Biochemical Marker Testing in Heart Failure. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .e99 B. Background and Definition of Terms . . . . . . . . . .e100 C. B-type Natriuretic Peptide (BNP) and AminoTerminal proB-Type Natriuretic Peptide (NT-proBNP) Metabolism and Measurement . . . .e100 I...
متن کاملNT-proBNP testing A valuable and cost-effective option for the diagnosis and management of heart failure The economic burden of heart failure NT-proBNP testing in the ED Improved diagnosis and stratification of patient care
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[Urinary measurement of N-terminal B type natriuretic peptide in patients with cardiac failure - highway or byway?].
Urine testing has the advantage of being convenient, familiar to a range of healthcare professionals, and non-invasive. Urine testing for albumin has a well-established role in the management of the diabetic patient and the assessment of renal disease. Urinary measurement of N-terminal B type natriuretic peptide (NTproBNP) has been proposed as a potential tool for detection of cardiac failure. ...
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