Subcortical hemorrhage in disseminated intravascular coagulation associated with sepsis.

Investigation Giant Placental Chorioangioma Associated with Neonatal Sepsis-like Disease: A Case Report

Giant chorioangioma is a placental tumor associated with gestational complications such as preeclampsia, polyhydramnios and hemorrhage. In addition, this tumor might lead to the incidence of non-immune fetal hydrops, heart failure, anemia, thrombocytopenia, weight loss and death among neonates. In this case report, the clinical image of a term newborn (weighing 2800 g) with one-minute Apgar sco...

Plasma Fibrinogen and D-dimer in Children With Sepsis: A Single-center Experience

Background & Objectives:  In sepsis, enhanced fibrin formation, impaired fibrin degradation, and intravascular fibrin deposition lead to a prothrombotic state. The current study aimed at measuring various coagulation parameters to predict an early marker for disseminated intravascular coagulation (DIC). Methods: The current prospective s...

Short Communication Successful treatment of sepsis-induced disseminated intravascular coagulation in a patient with idiopathic thrombocytopenic purpura using recombinant human soluble thrombomodulin

Purpura Fulminans in Infantile Streptococcal Septicemia

Purpura fulminans is a hemorrhagic condition associated predominantly with meningococcal and other gram negative septicemias. It occurs mainly in infants and younger children. Features include tissue necrosis, small vessel thrombosis, disseminated intravascular coagulation, multi-organ failure and death. Other causes include clotting factor deficiencies and idiopathic varieties. The condition i...

Recent acquisitions in the pathophysiology, diagnosis and treatment of disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC) is a disorder characterized by both acute generalized, widespread activation of coagulation, which results in thrombotic complications due to the intravascular formation of fibrin, and diffuse hemorrhages, due to the consumption of platelets and coagulation factors. Systemic activation of coagulation may occur in a variety of disorders, including sep...