IN-DEPTH REVIEW Prevention of laboratory animal allergy
نویسنده
چکیده
Laboratory animal allergy (LAA) is a common health problem in pharmaceutical research workers. The aetiology of LAA is well established and it is generally accepted that approximately one-third of exposed people may develop symptoms of LAA—see review articles [1,2]. The most common symptoms are rhinitis, conjunctivitis and contact urticaria; ~10% of workers may experience the most serious symptom of asthma. A personal history of allergy to common environmental allergens (atopy) and exposure to the animals are considered the most important risk factors for the development of allergy. What is of concern is that despite this knowledge, there continues to be a high prevalence of this disease throughout the western world [3–7]. This article will therefore focus on strategies for the prevention of LAA. Method
منابع مشابه
Mechanism and epidemiology of laboratory animal allergy.
Laboratory animal allergy (LAA) is a form of occupational allergic disease. The development of laboratory animal allergy is due to the presence of IgE antibodies directed against animal proteins. The process of sensitization (development of IgE antibodies) is a complex process which involves interaction of antigen presenting cells and lymphocytes of the Th-2 cell type. These cells generate a ho...
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