Evaluation of hepatoprotective effect of methanolic extract of Clitoria ternatea (Linn.) flower against acetaminophen-induced liver damage

نویسندگان

  • Kuppan Nithianantham
  • Kwan Yuet Ping
  • Lachimanan Yoga Latha
  • Subramanion L Jothy
  • Ibrahim Darah
  • Yeng Chen
  • Ai-Lan Chew
  • Sreenivasan Sasidharan
چکیده

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, 11800, Pulau Pinang, Malaysia School of Biological Sciences, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia Dental Research & Training Unit, and Oral Cancer Research and Coordinating Centre (OCRCC), Faculty of Dentistry, University of Malaya, 50603, Kuala Lumpur, Malaysia Asian Pac J Trop Dis 2013; 3(4): 314-319

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منابع مشابه

Hepatoprotective potential of Clitoria ternatea leaf extract against paracetamol induced damage in mice.

BACKGROUND AND AIM Clitoria ternatea, a medicinal herb native to tropical equatorial Asia, is commonly used in folk medicine to treat various diseases. The aim of the present study is to evaluate the hepatoprotective and antioxidant activity of C. ternatea against experimentally induced liver injury. METHODS The antioxidant property of methanolic extract (ME) of C. ternatea leaf was investiga...

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Comparative Evaluation of Hepatoprotective Potential of roots of Blue and white flowered varieties of Clitoria ternatea Linn

Pet Ether, Chloroform, and Methanol extracts of roots of Blue and White flowered varieties of Clitoria ternatea (CT) were studied for their hepatoprotective potential against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. The hepatoprotective activity was assessed using various biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate tr...

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Hypoglycemic Effects of Clitoria ternatea Linn. (Fabaceae) in Alloxan-induced Diabetes in Rats

Purpose: This study aims to investigate the therapeutic effects of the aqueous extract of Clitoria ternatea Linn. Fabaceae leaves and flowers on alloxan-induced diabetes in rats. Methods: The effect of orally administered aqueous extracts (400 mg/kg body weight) of Clitoria ternatea leaves and flowers on serum glucose, glycosylated hemoglobin, and insulin were examined in control and extract-tr...

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Eryngium Bungei Boiss Extract Has Hepatoprotective Effect Against Liver Damage Induced by Acetaminophen in Rats: Novel Antioxidant and Anti-Inflammatory Effects

Background: Acetaminophen-induced toxicity is a common cause of acute liver failure. This study investigated the hepatoprotective effects of Eryngium bungei Boiss (EB) extract against the hepatotoxicity in rats. Methods: Thirty adult male rats were randomly assigned to five groups, with free access to water and food. They were treated as follows: Group 1 (negative controls): distilled water ...

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Antioxidant and hepatoprotective effects of Clitoria ternatea leaf extracts by using in vivo model

Herbal medicines are in great demand because of their great efficacy and little or no side effects. Many plant extracts show promising antioxidant and free radical scavenging activity. The plant used in the present study is Clitoria ternatea (Sanskrit-Sankupushpam) belongs to the family Fabaceae . The in vivo studies were conducted using male Wistar rats. Liver cells participate in a variety of...

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تاریخ انتشار 2013