History of Thrombolytic Agents
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چکیده
Thrombolytics recanalize thrombotic occlusion associated with STsegment elevation myocardial infarction (STEMI) and restoration of coronary flow reduces infarct size and improves myocardial function and survival over the short-term and long-term. Thrombolytic therapy for acute myocardial infarction (AMI) was incorporated into the armamentarium of clinicians over 2 decades ago, and has evolved from first generation thrombolytic—streptokinase (SK) to newer thrombolytics such as alteplase (t-PA), reteplase (rPA) and tenecteplase (TNK). This article provides an overview of the various thrombolytic agents utilized in the management of patients with AMI.
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موانع موجود در شروع به موقع درمان ترومبولیتیک در بیماران مبتلا به سکته مغزی
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