BioE 332 Assignment 1: Persistent activity in a spatial working memory model
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چکیده
In this assignment we will build a cortical network model that captures neuronal persistent activity, similar to the persistent activity recorded in the prefrontal cortex of animals performing a spatial working memory task. We will see how stable activity patterns emerge from the recurrent network dynamics and persist on time scales greatly exceeding biophysical time constants of constituent neurons and synapses. In the language of dynamical systems, the spatial working memory model implements a line attractor. We will explore the sensitivity of this line attractor to the spiking noise and to the heterogeneity of the network parameters. By completion of this assignment, we will learn and understand the following:
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