Review on the Pharmacological Activities of Hydrazones derivatives 280

Hydrazones and their derivatives constitute a versatile class of compounds in organic chemistry. The development of novel hydrazones containing compounds possess a wide verities of biological activities like as antioxidant, anti-inflammatory, anticonvulsants, antidepressant and anxiolytic, antihypertensive, anticancer, antimicrobial, anti-tuberculosis, and antifungal activity. Hydrazones possess –NHN=CHand more significant for the development of novel drugs. Both nitrogen atoms of the hydrazone group are nucleophilic, although the amino type nitrogen is more reactive. Whereas, the carbon atom of hydrazone group has both electrophilic and nucleophilic. Subsequently, hydrazone derivatives more selective activity and lower side effect continues to be an active area of intensification in medicinal chemistry. This review is compiled which elaborate the medicinal importance and their biological properties.