The small peptide-catalyzed direct asymmetric aldol reaction in water.
نویسندگان
چکیده
Simple modular di- and tripeptides with a primary amine at the N-terminus catalyze the aqueous asymmetric aldol reaction between unmodified ketones and aldehydes to furnish the corresponding beta-hydroxy ketones with up to 86% ee in water and 99% ee in aqueous media.
منابع مشابه
Chitosan Aerogel Catalyzed Asymmetric Aldol Reaction in Water: Highly Enantioselective Construction of 3-Substituted-3-hydroxy-2-oxindoles
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 4 1 شماره
صفحات -
تاریخ انتشار 2006