Bedside diagnosis of alcohol intoxication with a pocket-size breath-alcohol device: sampling from unconscious subjects and specificity for ethanol.

Translational Antidote Research: A Bedside to Bench Tale

Although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. The development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an example of how this may not be the case. Interest in the development of fomepizole was spurred in the 1960s. Shortly t...

Use of a pocket-size breath analyzer in the detection and treatment of alcohol misuse.

Alcohol intoxication at Swedish football matches: A study using biological sampling to assess blood alcohol concentration levels among spectators

Alcohol use and alcohol-related problems, including accidents, vandalism and violence, at sporting events are of increased concern in Sweden and other countries. The relationship between alcohol use and violence has been established and can be explained by the level of intoxication. Given the occurrence of alcohol use and alcohol-related problems at sporting events, research has assessed intoxi...

Does Ingestion of Tincture of Opium Notably Raise Blood Alcohol Concentration?‎

Background: Tincture of opium (TOP) is currently used for maintenance therapy in treatment of opioids addiction. It contains ethanol. The present study was conducted to assess the increase in blood alcohol concentration (BAC) in its users; a process which may interfere with breath-alcohol test performed by law enforcement or traffic police. Methods: A total of 143 individuals were selected rand...

Dilemma of a Constant Blood/breath Ratio of Ethanol in Chemical Test Evidence of Intoxication

The notion of a constant blood/breath ratio of ethanol for all subjects under all conditions of testing continues to cause litigation and debate when results of breath analysis are used as evidence of impairment. A person's apparent blood/breath ratio depends on a host of factors that cannot be adequately controlled in forensic practice. Among others, the source of blood analyzed; artery, capil...