The Morris-Lecar neuron model embeds a leaky integrate-and-fire model.

نویسندگان

  • Susanne Ditlevsen
  • Priscilla Greenwood
چکیده

We show that the stochastic Morris-Lecar neuron, in a neighborhood of its stable point, can be approximated by a two-dimensional Ornstein-Uhlenbeck (OU) modulation of a constant circular motion. The associated radial OU process is an example of a leaky integrate-and-fire (LIF) model prior to firing. A new model constructed from a radial OU process together with a simple firing mechanism based on detailed Morris-Lecar firing statistics reproduces the Morris-Lecar Interspike Interval (ISI) distribution, and has the computational advantages of a LIF. The result justifies the large amount of attention paid to the LIF models.

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عنوان ژورنال:
  • Journal of mathematical biology

دوره 67 2  شماره 

صفحات  -

تاریخ انتشار 2013