Olanzapine-Induced Neutropenia
نویسندگان
چکیده
Olanzapine-induced neutropenia is a rare adverse effect that is currently poorly described in literature. Although neutropenia is a known adverse effect of clozapine, it has been associated with the use of other antipsychotic medications like olanzapine. This case report describes and reviews a case of olanzapine-induced neutropenia in a schizophrenic patient. Although the mechanism of antipsychotic-induced neutropenia is still debated, this report attempts to discuss current theories as well as supply evidence in literature of this rare but potentially dangerous adverse effect.
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O presente re la to é compat íve l com a hipótese de Thangadurai et al. descrita acima, mas sugere que a susceptibilidade à neutropenia após exposição à clozapina pode ser transitória, de modo que o r isco hematológico da olanzapina decresceria à medida que o tempo decorrido após a suspensão da clozapina aumentasse. Sugerimos que pacientes que desenvolverem alterações hematológicas com clozapin...
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