Gold-catalyzed intramolecular diazo coupling: an efficient macrocyclization towards cyclic olefins.
نویسندگان
چکیده
A gold-catalyzed intramolecular coupling of diazo compounds to produce cyclic olefins has been well established. The medium and large sized membered olefins were obtained in moderate to good yields. Notably, the Z/E selectivity of the olefins highly depended on the ring size. Furthermore, this investigation indicated that the structure of the phosphorous ligand binding to the gold centre played a vital role in the reaction efficiency. Also, high dilution of the reaction mixture is not needed.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 64 شماره
صفحات -
تاریخ انتشار 2015