Enantioselective synthesis of allenamides via sulfimide [2,3]-sigmatropic rearrangement.
نویسندگان
چکیده
Chiral allenamides are prepared with high levels of enantiomeric purity by [2,3]-sigmatropic rearrangement of propargylic sulfimides. The required branched propargylic sulfides are prepared by an enantioselective organocatalytic aldehyde alpha-sulfenylation followed by Corey-Fuchs alkynylation.
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ورودعنوان ژورنال:
- Organic letters
دوره 11 7 شماره
صفحات -
تاریخ انتشار 2009