Chairs of WCSB

S ........................................................................................................................................... 19 Systemic Integration and Exploration of Genomic Variants Jake Lin and Patrick May ...................................................................................................................... 20 Integrative Studies of Allosteric Regulation in Signal Transduction Networks: a Synergistic Perspective From Computational Systems Biology and Proteomics Approaches Kristin Blacklock and Gennady Verkhivker ........................................................................................... 21 Design Space Analysis Supports Role of Peroxiredoxin/Thioredoxin/Thioredoxin-Reductase System in Integrating Redox Signaling And Anticipatory Blocking Gianluca Selvaggio, Pedro Coelho and Armindo Salvador ................................................................... 22 Identification of Signalling Mediators Vincenzo Belcastro ............................................................................................................................... 23 Parameter inference for stochastic models: A comparison of multiple shooting for stochastic systems to conventional least squares Christoph Zimmer and Sven Sahle ........................................................................................................ 24 Multivariate moment closure techniques for stochastic kinetic models Eszter Lakatos, Paul Kirk and Michael P. H. Stumpf ............................................................................. 25 Optimal Observation Time Points in Stochastic Chemical Kinetics Charalampos Kyriakopoulos and Verena Wolf ..................................................................................... 26 Distribution reconstruction for stochastic chemical kinetics from conditional moment data Alexander Andreychenko, Linar Mikeev and Verena Wolf ................................................................... 27 Sensitivity analysis and parameter estimation of a human blood glucose regulatory system model Domokos Meszéna, Eszter Lakatos and Gabor Szederkenyi ................................................................ 28 Computational Model of Fgf2 Signalling Network In Human Embryonic Stem Cells Revealed Oxygen Triggered Metabolic Switch Anton Salykin, Dominique Chu, Petr Fojtik, Miriama Kruta, Katka Schrammova, Petr Skladal, Petr Dvorak and Vladimir Rotrekl ................................................................................................................ 29 Image Alignment and Lineage Construction Tool to Study Segregation and Partitioning in Division of Unwanted Protein Aggregates in Escherichia Coli João Santinha, Antti Häkkinen, Abhishekh Gupta, Teppo Annila, Jason Lloyd-Price, Andre S. Ribeiro and José Fonseca .................................................................................................................................. 30 Generator of Synthetic Time-Lapsed, Phase-Contrast Microscopy Images of Growing E. Coli Cell Populations Leonardo Martins, Andre S. Ribeiro and Jose Fonseca ........................................................................ 31 Detecting Genetic Interactions in Case-Control Data: Information Theory Based Methods Tomasz Ignac, Alexander Skupin, Nikita Sakhanenko and David Galas ................................................ 32 Microorganism's Growth-Robustness Trade-Off Explained by Simple General Principles Alessandro Bolli and Armindo Salvador ............................................................................................... 33 In Vivo Retention of Protein Aggregates in Escherichia Coli Nadia Goncalves, Ramakanth Neeli Venkata, Antti Martikainen, Joao Santinha, Jose Fonseca and Andre Ribeiro ........................................................................................................................................ 34 Analysis of The Robustness of a Single Copy Repressilator Samuel M.D. Oliveira, Jerome G. Chandraseelan, Antti Häkkinen, Olli Yli-Harja and Andre S. Ribeiro .................................................................................................................................... 35 Estimating the Duration of Open Complex Formation From in Vivo Measurements Jerome G. Chandraseelan, Jason Lloyd-Price, Olli Yli-Harja and Andre S. Ribeiro ................................ 36 In Silico Screening of Lead-Like Molecules en Route to Antitumor and Antibiotic Drugs from Marine and Microbial Natural Products Using Empirical and Semi-Empirical Quantum-Chemical Descriptors Florbela Pereira, Diogo A. R. S. Latino and Susana P. Gaudêncio ......................................................... 37 INVITED TALKS Workshop on Computational Systems Biology 2014, May 15-16, Lisbon, Portugal