A Hierarchical Model for Probabilistic Dose-Response Assessment of Bacillus anthracis
نویسندگان
چکیده
Altboum, Z., Y. Gozes, A. Barnea, A. Pass, M. White, and D. Kobiler 2002. Post exposure prophylaxis against anthrax: Evaluation of various treatment regimens in Intranasally infected guinea pigs. Infection and immunity 70:6231. Druett, H.A., D.W. Henderson, L. Packman, and Sory Infection with Anthrax Spores. Journal of Hygiene 51:359. Haas, C.N., 2002. On the risk of mortality to primates exposed to anthrax spores. Risk Analysis 22:2:189. Pitt, M.L.M., S.F. Little, B.E. Ivins, P. Fellows, J. Barth, J. Hewetson, P. Gibbs, M. Dertzbaugh, A.M. Friedlander. 2001. In vitro correlate of immunity in a rabbit model of inhalation anthrax. Vaccine 19:4768. Future work
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Evaluation the Efficacy of Anthrax Vaccine against Challenge with a Highly Virulent Strain of Bacillus anthracis Isolated from Soil in Sheep, Goats and Guinea Pigs in Iran
Protection of animals immunized against Bacillus anthracis is usually demonstrated by challenging with an appropriate dose of a strain of Bacillus anthracis that is lethal to unvaccinated animals inoculated at the same time. In this study the protective efficacy in anthrax vaccine (34F2 sterne strain spore) was evaluated in sheep, goats and guinea pigs challenged with subcutaneous inoculation...
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