Effects of fullerene derivatives on bioluminescence and application for protease detection.
نویسندگان
چکیده
The effects of two C(60) derivatives: C(60)[C(COOH)(2)](3) and C(60)(NH(2))(x)(OH)(y), have been investigated on the bioluminescence of humanized Gaussia luciferase (hGluc) for the first time. Utilizing the dual properties of carboxyl C(60) with luminescence quenching and free radicals scavenging, a novel BRET system was constructed for protease detection with high sensitivity.
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عنوان ژورنال:
- Chemical communications
دوره 48 89 شماره
صفحات -
تاریخ انتشار 2012