Current Concepts in Adult CRPS.

C RPS is a pa infu l con d ition which usually dev elops after trauma to a limb . It is chnracrerbed by l imb_confln~-d sensory, autonomic, moto r, skin and bon e cha nges, btu the lead symptom is pain. Earlier names for the condi tion are given in appendix A. 111e C Rrs diagno stic crite ria have recently been up dated ('Budape sr Criteria", appendi x B}, because earlier criteria were nor specific . These new criteria, although widely used have nOI yet been formally ado pted by rhe Int ernational Associati on for the Stud y of Pain ( I) . O ver the past 10 years many investigators , scient ists an d clini cians alike have jointl y ach ieved remarkable progress in understanding and treating C RPS. These efforts have been enhanced by the success of the 'TREN D" consort ium led by Prof. J.J. van Hilren from Leiden and Prof. van der Helm from Delft , who secured in the early 2000's over 20 million Eurc in research suppo rr from the Durch M inisrry of Econ omic Affairs to study CRPS and related cond itio ns.