A general protein purification and immobilization method on controlled porosity glass: biocatalytic applications.

نویسندگان

  • K Engelmark Cassimjee
  • M Kadow
  • Y Wikmark
  • M Svedendahl Humble
  • M L Rothstein
  • D M Rothstein
  • J-E Bäckvall
چکیده

A general combined purification and immobilization method to facilitate biocatalytic process development is presented. The support material, EziG™, is based on controlled porosity glass (CPG) or polymer-coated versions thereof (HybCPG) and binds protein affinity tags. Biocatalytic reactions in aqueous and organic media with seven enzymes of biocatalytic interest are shown.

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عنوان ژورنال:
  • Chemical communications

دوره 50 65  شماره 

صفحات  -

تاریخ انتشار 2014