On the Deenition and the Construction of Pockets in Macromolecules
نویسندگان
چکیده
The shape of a protein is important for its functions. This includes the location and size of identiiable regions in its complement space. We formally deene pockets as regions in the complement with limited accessibility from the outside. Pockets can be eeciently constructed by an algorithm based on alpha complexes. The algorithm is implemented and applied to proteins with known three-dimensional conformations.
منابع مشابه
Comparison of the efficacy of Matrica and %0.2 Chlorhexidine mouthwashes on 3-6 mm pockets in patients with chronic periodontitis
Comparison of the efficacy of Matrica and %0.2 Chlorhexidine mouthwashes on 3-6 mm pockets in patients with chronic periodontitis Dr. M. Paknejad* - Dr. TS. Jafarzadeh** - Dr. AM. Shamloo*** *- Associate Professor of Periodontics Dept. - Faculty of Dentistry – Tehran University of Medical Sciences. **- Assistant Professor of Dental Materials Dept. Faculty of Dentistry – Tehran University of Med...
متن کاملOn the Definition and the Construction of Pockets in Macromolecules
The shape of a protein is important for its functions. This includes the location and size of identifiable regions in its complement space. We formally define pockets as regions in the complement with limited accessibility from the outside. Pockets can be efficiently constructed by an algorithm based on alpha complexes. The algorithm is implemented and applied to proteins with known three-dimen...
متن کاملPeriodontal Pockets as a Potential Source of Infection: a Case of Possible Odontogenic Septic Pulmonary Embolism
Although dental foci can be sources of bacteremia and bacterial endocarditis, hematogenous spread of infection presented with septic pulmonary embolism apparently is rare. The occurrence of septic pulmonary embolism in patients with periodontal disease without suppurative thrombophlebitis of the great vessels of the neck is well documented but to our knowledge, there is no report on septic pulm...
متن کاملUsing a Temperature Gradient against the Time in Polyacrylamide Gel Electrophoresis May Eliminate the Need for Stacking Gels
Background and Objectives: Making stacking gels for polyacrylamide gels in the laboratory by conventional methods is laborious and time consuming. Considering the role of temperature in polyacrylamide gels with respect to electrical resistance and viscosity, we assumed that decreasing the temperature would cause an increase in electrical resistance and viscosity. Ultimately, a downward tempera...
متن کاملInteraction of Cisplatin with Cellular Macromolecules: A Fourier Transform Infrared Spectroscopy Study
Platinum is a metallic element, which may react with our cellular component through its involvement in cancer chemotherapy medications. Cisplatin is one of the most useful antineoplastic drugs against human ovarian carcinoma, which has the central element of platinum in its structure. The nature of chemical interaction between platinum and cellular macromolecules is yet to be understood. We exa...
متن کامل