Synthesis and characterization of multifunctional gold nanoclusters for application in radiation therapy

نویسندگان

  • Richa Baronia
  • Manjri Singh
  • Rajat B Gupta
  • Stalin Karuppiah
  • Rajiv Kumar
  • Jodi Belz
  • Rishi Shanker
  • Srinivas Sridhar
  • Surinder P Singh
چکیده

Gold nanoparticles, because of their high radiation absorption coefficient and efficient generation of secondary photoelectrons, have been predicted to enhance therapeutic efficacy in radiation therapy. However, high dose for effective treatment limits their use. We have synthesized multifunctional gold nanoclusters (GNCs) that can be used for imaging and radiation therapy. The designed GNCs have been characterized for their physicochemical properties, biocompatibility, and their radiation dose enhancement potential on PC3 cell lines.

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عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2018