AFM-Raman Characterization of Pharmaceutical Tablets
نویسندگان
چکیده
It is also useful in revealing the presence of impurities and structural disorder in materials, studying stress distributions, and temperature effects. Integration of Raman spectroscopy with Atomic Force Microscopy (AFM) opens a wide range of new capabilities in imaging and characterizing pharmaceutical products. For example, AFM topographic imaging provides information on the size of grains, their shape, orientation and distribution. In addition, advanced AFM techniques also allow high resolution imaging of various physical properties of micro-scale objects: local hardness, friction coefficient, electrical conductivity, surface potential and many others.
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