Co-abuse of opiates and benzodiazepines.

نویسندگان

  • S Rooney
  • G Kelly
  • L Bamford
  • D Sloan
  • J J O'Connor
چکیده

The objective of the study was to assess what differences exist between individuals who are dependent on opiates and benzodiazepines and compare to those who are dependent on opiates. A questionnaire was compiled and administered to patients who had been consecutively admitted to an inpatient drug treatment unit. The prevalence of benzodiazepine dependency was 54 per cent [n = 34]. Patients dependent on benzodiazepines and opiates were significantly older, had been admitted for methadone stabilisation and were more likely to have been prescribed a methadone maintenance programme prior to admission. They had used heroin longer, benzodiazepines more frequently, at larger doses for a longer duration of time and tended to use more drugs in general. They were found to be more psychologically vulnerable than those not dependent on benzodiazepines as they were significantly more likely to have described a past experience of depression and a past episode of deliberate self harm.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Detection of benzodiazepine abuse in opiate addicts.

There is an increasing problem with benzodiazepine co-abuse in the opiate dependent population of Dublin. The importance of early detection of this co-abuse is essential as there is an increased risk of dangerous injecting practices such as sharing of needles and criminality in those who co-abuse benzodiazepines and opiates. This study was carried out in the National Drug Treatment Centre, Dubl...

متن کامل

In vitro UGT assay for inhibition studies of benzodiazepines and opiates during phase II-metabolism

Hydroxy-benzodiazepines and opiates are metabolized through glucuronidation which is the predominant pathway in the clearance mechanism of exogenous and endogenous substances during phase II-metabolism. The reaction is catalyzed by uridine-diphosphoglucuronyltransferases (UGTs) [1]. The presented work is motivated by the fact that the combination of benzodiazepines and opiates is common both in...

متن کامل

Interference of common household chemicals in immunoassay methods for drugs of abuse.

I report how some adulterants affect results for drugs of abuse in urine as measured by Roche RIA, Syva emit d.a.u., and Abbott TDx fpia (fluorescence polarization immunoassay) for the following drugs: amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, opiates, and phencyclidine (PCP). Sodium chloride interfered negatively with all of these drugs when assayed by emit and caused...

متن کامل

زنان باردار با سوءمصرف مواد

Substance abuse is a major health problem that has adverse consequences on social groups, especially it puts pregnant women at a serious risk. Currently, increased rate of pregnancy in women with substance abuse is a serious concern for the health care system. History of substance abuse and trauma, avoidance of or poor access to prenatal care, and concern about legal consequences of substance a...

متن کامل

Nonmedical Abuse of Benzodiazepines in Opiate-Dependent Patients in Tehran, Iran

OBJECTIVE The purpose of the present preliminary study was to explore the prevalence of nonmedical abuse of benzodiazepines in a group of opiate-dependent patients who were on methadone maintenance treatment (MMT) program in outpatient clinics in the south-west of Tehran, Iran. METHODS 114 male and female opiate-dependent clients who met DSM.IV-TR criteria for opiate dependence with mean age ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Irish journal of medical science

دوره 168 1  شماره 

صفحات  -

تاریخ انتشار 1999