Tumor angiogenesis is caused by single melanoma cells in a manner dependent on reactive oxygen species and NF-kB

Maximilian K. Schaafhausen, Wan-Jen Yang, Lazaro Centanin, Joachim Wittbrodt, Anja Bosserhoff, Andreas Fischer, Manfred Schartl and Svenja Meierjohann* Department of Physiological Chemistry I, Biocenter, Am Hubland, University of Wurzburg, Wurzburg, Germany Vascular Signaling and Cancer, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany Vascular Biology, Medical Faculty Mannheim (CBTM), Heidelberg University, Mannheim, Germany Centre for Organismal Studies, University of Heidelberg, Heidelberg, Germany Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany Institute of Pathology, University of Regensburg, Regensburg, Germany Comprehensive Cancer Center Mainfranken, University Hospital Wurzburg, Germany