Protection of mice against Listeria monocytogenes infection by recombinant human tumor necrosis factor alpha.
نویسندگان
چکیده
Recombinant human tumor necrosis factor alpha (rHuTNF-alpha) administered intravenously to mice resulted in enhanced resistance to a lethal challenge infection of Listeria monocytogenes given 24 h later. The observed protection was lost following treatment of the rHuTNF-alpha preparations with rabbit polyclonal antibody rHuTNF-alpha but not with normal rabbit immunoglobulin G.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 57 5 شماره
صفحات -
تاریخ انتشار 1989