Functional analysis of the human RNASET2 gene: non-cell autonomous tumor suppression and putative stress-induced cell autonomous roles
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منابع مشابه
Pleiotropic modes of action in tumor cells of RNASET2, an evolutionary highly conserved extracellular RNase
As widely recognized, tumor growth entails a close and complex cross-talk among cancer cells and the surrounding tumor microenvironment. We recently described the human RNASET2 gene as one key player of such microenvironmental cross-talk. Indeed, the protein encoded by this gene is an extracellular RNase which is able to control cancer growth in a non-cell autonomous mode by inducing a sustaine...
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