Improved Results Using Decellularized Human Valves for Children with Congenital Heart Defects

نویسندگان

  • Bahar Söylen
  • Samir Sarikouch
  • Alexander Horke
چکیده

For decades the most common therapeutic option for young patients with severe valve disease due to a congenital heart defect has been a biological valve replacement, which undergoes degenerative processes and therefore inevitably leads to reoperations within five to ten years [1-3]. Children especially require earlier re-interventions due to stronger immunological reactions to the grafts [4-8] resulting in early calcification [9,10].

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Prevalence of Celiac Disease in Down syndrome Children with and without Congenital Heart Defects

Background The prevalence of celiac disease (CD) is remarkably varied in Down syndrome(DS)patientscompared with other diseases.  This study aimed to assess celiac disease prevalence in Down syndrome children with and without congenital heart defects (CHD) and its comparison with controls. Materials and Methods This case-control study was performed at a single center on 132 participants in three...

متن کامل

بررسی کودکان مراجعه کننده به مرکز طبی کودکان با تشخیص بیماری های مادرزادی قلب 80-1379

The most common congenital diseases in children is congenital heart disease. Factors such as environment, genetic, old maternal age during pregnancy, maternal disease and using medicine in pregnancy, prematuritiy, and specific seasons are significant in the prevalence of disease.Materials and Methods: A cross sectional study was conducted to investigate the status of children with congenital he...

متن کامل

Congenital Heart Defects in Children with Dextrocardia: A Ten-Year Study

Background Dextrocardia is a malposition of the heart defined as the right-sided development of the heart. It can increase the likelihood of congenital heart defects or diseases (CHD) and the risk of related morbidities and mortalities. We aimed to determine the frequency of CHDs among Dextrocardia patients. Materials and Methods In a retrospective cross-sectional study the records of patients ...

متن کامل

Tissue engineering of heart valves: decellularized porcine and human valve scaffolds differ importantly in residual potential to attract monocytic cells.

BACKGROUND Tissue-engineered or decellularized heart valves have already been implanted in humans or are currently approaching the clinical setting. The aim of this study was to examine the migratory response of human monocytic cells toward decellularized porcine and human heart valves, a pivotal step in the early immunologic reaction. METHODS AND RESULTS Porcine and human pulmonary valve con...

متن کامل

Study of the Association between Congenital Heart Defects and Neuroblastoma in Abdominal Sonography

Abstract Background A higher prevalence of congenital heart defects (CHD) in neuroblastoma patients in general population is reported in some publications, however, some authors did not find such an association. The evidence for this relation comes from the observation that, the neural crest cells accompany to the development of the heart and neuroblastoma as well. Materials and Methods We...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017