A new norlignan from Taxodium ascendens.

نویسندگان

  • Yu Mei Zhang
  • Ning Hua Tan
  • Guang Zhi Zeng
  • Abiodun Humphrey Adebayo
  • Chang Jiu Ji
چکیده

A new norlignan, (2R,3R,4S,5S)-2,4-bis(4-hydroxyphenyl)-3,5-dihydroxy-tetrahydropyran (1), together with 9 known compounds were isolated from the branches and leaves of Taxodium ascendens. Their structures were mainly determined on the basis of MS, IR, 1D and 2D NMR spectral evidences. Methanol extract showed inhibitory activity on carbonic anhydrase II with an IC(50) value of 4.27 microg/ml, acetone extract and methanol extract inhibited activity of cathepsin B with IC(50) values of 2.12 and 3.71 microg/ml, respectively.

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عنوان ژورنال:
  • Fitoterapia

دوره 80 6  شماره 

صفحات  -

تاریخ انتشار 2009