MALDI-TOF MS Coupled with Collision-Induced Dissociation (CID) Measurements of Poly(methyl methacrylate)
نویسندگان
چکیده
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) is one of themost fundamental analysis techniques for proteins, peptides, and synthetic polymers to date. Along with field desorption (FD), fast atom bombardment (FAB), laser desorption coupled with time-of-flight (LD-TOF), secondary ion mass spectrometry coupled with time-of-flight (SIMS-TOF), and electron spray ionization (ESI), it is one of the softest ionization methods available. The main limitation for most mass spectrometry techniques consists in their applicability being limited to synthetic polymers with relatively low molar masses (<5 000 Da). MALDI, on the Communication
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