Blood smear, a key diagnostic tool in hematology: Lessons from two cases of acute hemolysis in previously undiagnosed G6PD deficiency.

نویسندگان

  • Dino Veneri
  • Davide Facchinelli
  • Alice Vianello
  • Achille Ambrosetti
  • Maurizio Cantini
  • Oliviero Olivieri
  • Francesco Dima
  • Lucia De Franceschi
چکیده

Image 1. Upper panels: Peripheral blood smears of case 1 (A) and 2 (B), showing marked anisopoikilocytosis, with formation of hemi-ghost blister cells (*) and presence of circulating erythroid precursors (insets). Lower panels: Respective values for hemoglobin (Hb), reticulocytes, platelets (PLTs), total white blood cell (WBC) count, bilirubin, lactate dehydrogenase (LDH), and creatinine levels during hospitalization. Black arrows indicate transfusion of packed red cells.

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Clinical Manifestations of Acute Hemolysis in Children with Glucose-6-Phosphate Dehydrogenase Deficiency in Fars Province, Iran

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CLINICAL PRESENTATION OF GLUCOSE-6- PHOSPHATE DEHYDROGENA SE (G6PD) DEFICIENCY: A PILOT STUDY

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A patient undergoing chemotherapy for relapsed non Hodgkin lymphoma developed tumor lysis syndrome, hypoxia and the abrupt onset of intravascular hemolysis. A past history of unexplained anemia and the finding of blister cells on peripheral smear led to the suspicion of congenital glucose phosphate dehydrogenase (G6PD) deficiency with intravascular hemolysis induced by the drug rasburicase. G6P...

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عنوان ژورنال:
  • American journal of hematology

دوره 91 11  شماره 

صفحات  -

تاریخ انتشار 2016