A novel multivalent tuberculosis vaccine confers protection in a mouse model of tuberculosis.
نویسندگان
چکیده
Mycobacterium tuberculosis infects one third of the world's population. Due to variable efficacy of the Bacille Calmette Guerin (BCG) vaccine, development of novel TB vaccines remains a priority. Here, we demonstrate the protective efficacy of a novel multivalent DNA vaccine, which contains 15 synthetic antigens targeting the Mtb ESX secretion system.
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ورودعنوان ژورنال:
- Human vaccines & immunotherapeutics
دوره 12 10 شماره
صفحات -
تاریخ انتشار 2016