Aptamer-based affinity labeling of proteins.

نویسندگان

  • Jan L Vinkenborg
  • Günter Mayer
  • Michael Famulok
چکیده

A most able label: Labeled aptamers can be cross-linked to their target structures in a light-dependent and highly specific manner as a result of a new strategy termed aptamer-based affinity labeling (ABAL) of proteins. The aptamer-protein complexes can be enriched in vitro, from a cellular lysate and from the surface of living cells, opening new ways to study aptamer interactions in biological contexts.

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عنوان ژورنال:
  • Angewandte Chemie

دوره 51 36  شماره 

صفحات  -

تاریخ انتشار 2012