Artificial dermis is not effective for resurfacing bone - exposing wounds ofGustilo ‒

1 According to the treatment of open fracture, the resurfacing of bone-exposing complex 2 wounds of Gustilo-Anderson III B and C fracture remains challenging. To treat 3 bone-exposing wounds, artificial dermis has been effective. We evaluated the 4 outcome of adapting artificial dermis the resurfacing bone-exposing complex wounds 5 of Gustilo-Anderson III B and C fracture clinically. Seven patients who had sustained 6 Gustilo-Anderson III B and C fracture of the legs underwent open reduction and Ilizarov 7 external fixation. The bone-exposing wounds were covered with slit artificial dermis, 8 and a basic fibroblast growth factor was sprayed every day. Wounds in all patients 9 showed insufficient granulation on the bone. Four patients developed osteomyelitis. 10 Consequently, all cases required a local flap for resurfacing the wounds. Although the 11 artificial dermis allows wounds to heal earlier, it is impossible to prepare a favorable 12 wound bed on the bone when the fracture is classified as Gustilo-Anderson III B and C. 13 We concluded that artificial dermis is not a recommendable resurfacing option for 14 patients with Gustilo-Anderson III B and C fracture because the poor circulation of 15 bone may result in osteomyelitis. 16