Supporting Text S1 Mismatch- and G-stack modulated probe signals on SNP microarrays
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Mismatch and G-Stack Modulated Probe Signals on SNP Microarrays
BACKGROUND Single nucleotide polymorphism (SNP) arrays are important tools widely used for genotyping and copy number estimation. This technology utilizes the specific affinity of fragmented DNA for binding to surface-attached oligonucleotide DNA probes. We analyze the variability of the probe signals of Affymetrix GeneChip SNP arrays as a function of the probe sequence to identify relevant seq...
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