Genomic Fold Assignment and Rational Modeling of Proteins of Biological Interest
نویسندگان
چکیده
The first available genome of a multicellular organism, C. elegans, was used as a test case for protein fold assignment using PSI-BLAST, followed by rational structure modeling and interpretation of experimental mutagenesis data in the context of collaboration with biologists. Similar results are demonstrated for human disease proteins with known polymorphisms.
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ورودعنوان ژورنال:
- Proceedings. International Conference on Intelligent Systems for Molecular Biology
دوره 8 شماره
صفحات -
تاریخ انتشار 2000