Studies on the hemolysin and agglutinin of leukemic leukocytes.

I x A RECENT STUDY of leukemic leukocyt-e extracts, the presence of an agglutinin and hemolysin active against trypsimsized erythrocytes was noted.1 The purpose of this report is to describe additional studies on this hemolysin and agglutinin. These studies have attempted to aisssver the following quest-ions: Is there any relationship between these agglutinins aisd hemolysins and the aist.ibodies responsible for the development of acquired hemolytie anemia?2 Are t hese agglut-inins and hensolysins related to -glucuronidase,3 ant-i-H material,4 01 to lytic material found in tumor tissue?5 During these studies, partial inhibitiois of the hemolytic and agglutinin activity by serum was noted, and an attempt has been made to characterize the meehanisns of inhibition.