Effect of lipid peroxidation on membrane permeability of cancer and normal cells subjected to oxidative stress.

Effect of lipid peroxidation on membrane permeability of cancer and normal cells subjected to oxidative stress† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc02311d Click here for additional data file.

Ferulic acid protects PC12 neurons against hypoxia by inhibiting the p-MAPKs and COX-2 pathways

Objective(s):Hypoxia induces cellular oxidative stress that is associated with neurodegenerative diseases. Here, the protective effects of ferulic acid (FA) on hypoxia-induced neurotoxicity in PC12 cells were evaluated. Materials and Methods:We investigated the effect of FA on PC12 cells subjected to hypoxia stress, in vitro. Results:FA increased cell viability, prevented membrane damage (LDH r...

Oxidative membrane damage and its involvement in gamma radiation-induced apoptotic cell death.

Background: Recent results have provided increasing evidence to support involvement of membrane damage in the mechanism of ionizing radiation induced killing of mammalian cells. These findings have stimulated renewed interest in evaluating the damage to membrane as a primary initiator in radiation-induced cell killing especially in apoptotic death. The present study was aimed to gain deeper ins...

Ameliorating effects of genestein: Study on mice liver glutathione and lipid peroxidation after irradiation

Background: Genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. Radiation–induced free radicals in turn impair the antioxidative defense mechanism, leading to an increased membrane lipid peroxidation that results in damage of the membrane bound enzyme and may lead to damage or death of cell. Hence, the lipid peroxidation is a good biomar...

Response of Fenugreek plants to short-term salinity stress in relation to lipid peroxidation, antioxidant activity and protein content

To investigate the effect of salinity stress on membrane stability index, membrane lipid peroxidation, catalase activity and protein content of Fenugreek (Trigonellafoenum) an experiment with five levels of short-term salinity stress (0, 50, 100, 150 and 200 mM) was carried out at the laboratory of agriculture faculty of Shahid Bahonar University of Kerman, Iran. The treatments were ar...