Characterization of Peste des Petits Ruminants Virus, Eritrea, 2002–2011
نویسندگان
چکیده
Figure. Distribution of ruminants in Eritrea with peste des petits ruminants virus infection, 2003–2011. Colored circles indicate regions from which tissue samples were collected from goats and sheep during outbreaks of peste des petits ruminants; nucleotide sequences for the samples were determined and analyzed.
منابع مشابه
Cloning of fusion (F) protein gene of peste des petits ruminants virus (PPRV) in secretory Pichia pastoris vector
With advent and development of DNA recombinant technology and advantages of p. pastoris expression system, fusion (F) protein of PPRV expression, because of effective immunodominant role could be an appropriate candidate for production of recombinant vaccine against PPR disease. In this study, F gene of PPRV Nigeria 75/1 strain (1637 bp) was amplified using RT-PCR and purified. It was then cl...
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We report the first complete genome sequence of a lineage III peste des petits ruminants virus (KN5/2011) using RNA extracted from goat lung tissue collected in Kenya in 2011. The genome shows the highest nucleotide sequence identity with lineage II peste des petits ruminants viruses (PPRVs) (86.1 to 87.2%) and the lowest with lineage IV PPRVs (82.5 to 83.8%).
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Small ruminants infected with peste des petits ruminants virus exhibit lesions typical of epithelial infection and necrosis. However, the only established host receptor for this virus is the immune cell marker signaling lymphocyte activation molecule (SLAM). We have confirmed that the ovine Nectin-4 protein, when overexpressed in epithelial cells, permits efficient replication of PPRV. Furtherm...
متن کاملSeroprevalence Study of Peste Des Petits Ruminants in Sheeps of Shabestar, Iran
Background Peste des petits ruminants (PPR) disease is one of the most important viral infections in sheep and goats that is caused by a morbillivirus from the paramixoviridae family, causing lesions in the gastrointestinal tract and respiratory tract. Methods In the present study, 250 blood samples were taken from the jugular vein of the apparently healthy and diseased sheep with common sympto...
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In May 2011 in Turkana County, north-western Kenya, tissue samples were collected from goats suspected of having died of peste des petits ruminant (PPR) disease, an acute viral disease of small ruminants. The samples were processed and tested by reverse transcriptase PCR for the presence of PPR viral RNA. The positive samples were sequenced and identified as belonging to peste des petits rumina...
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