Inducing a Normal Phenotype in Breast Epithelial Cells Using a Three-Dimensional Basement Membrane Extract Culture System: A Study on the Reversion of Cancer
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چکیده
Inducing a Normal Phenotype in Breast Epithelial Cells Using a ThreeDimensional Basement Membrane Extract Culture System: A Study on the Reversion of Cancer
منابع مشابه
Modeling Breast Acini in Tissue Culture for Detection of Malignant Phenotype Reversion to Non-Malignant Phenotype
Backgrounds: Evidence is accumulating to support disruption of tissue architecture as a powerful event in tumor formation. For the past four decades, intensive cancer research with the premise of “cancer as a cell based-disease” focused on finding oncogenes or tumor suppressor genes. However, the role of the tissue architecture was neglected. Three dimensional (3D) cell cultures which can recap...
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