Electrochemical Disinfection of Dental Implants – a Proof of Concept
نویسندگان
چکیده
BACKGROUND Peri-implantitis has gained significant clinical attention in recent years. This disease is an inflammatory reaction to microorganisms around dental implants. Due to the limited accessibility, non-invasive antimicrobial strategies are of high interest. An unexpected approach to implant disinfection may evolve from electrolysis. Given the electrical conductivity of titanium implants, alkalinity or active oxidants can be generated in body fluids. We investigated the use of dental titanium implants as electrodes for the local generation of disinfectants. Our hypothesis was that electrolysis can reduce viable counts of adhering bacteria, and that this reduction should be greater if active oxidative species are generated. METHODOLOGY/PRINCIPAL FINDINGS As model systems, dental implants, covered with a mono-species biofilm of Escherichia coli C43, were placed in photographic gelatin prepared with physiological saline. Implants were treated by a continuous current of 0-10 mA for 15 minutes. The reduction of viable counts was investigated on cathodes and anodes. In separate experiments, the local change in pH was visualized using color indicators embedded in the gelatin. Oxidative species were qualitatively detected by potassium iodide-starch paper. The in situ generated alkaline environment around cathodic implants caused a reduction of up to 2 orders of magnitude in viable E. coli counts. On anodic implants, in contrast to cathodic counterparts, oxidative species were detected. Here, a current of merely 7.5 mA caused complete kill of the bacteria. CONCLUSIONS/SIGNIFICANCE This laboratory study shows that electrochemical treatment may provide access to a new way to decontaminate dental implants in situ.
منابع مشابه
Economic comparison of conventional maintenance and electrochemical oxidation to warrant water safety in dental unit water lines
BACKGROUND In preparation for implementation of a central water processing system at a dental department, we analyzed the costs of conventional decentralized disinfection of dental units against a central water treatment concept based on electrochemical disinfection. METHODS The cost evaluation included only the costs of annually required antimicrobial consumables and additional water usage o...
متن کاملThe Effect Of Restoration Type On Osseointegration of Dental Implants: A Histological Analysis In Dogs
Background and Objective: The concept of immediate occlusal loading with dental implants offers several advantages. In this research, the effect of type of restoration on Osseointegration rate of dental implants was histologically evaluated. Materials and Methods: Three months prior to implantation, the lower premolar teeth of 15 dogs were extracted. Then, 3 to 4 Maestro™ implants were plac...
متن کاملComparison of the Effect of Perchlorine, Sodium Hypochlorite, and Electrochemical Method on Disinfection of Vegetables
Introduction: Many vegetables are eaten raw which can lead to the prevalence of food borne diseases if not properly sanitized. The aim of this study was to compare the effect of chlorine, bleach and multioxidant solution in disinfection of edible vegetables. Materials and Methods: In this experimental study, 100 g of vegetables (lettuce, basil and mint) was disinfected by sodium hypochlorite, ...
متن کاملElimination of pathogenic bacteria using electrochemical process containing steel mesh electrode
The main objective of this study is removal of pathogenic bacteria using electrochemical process. The bactericidal effects of electrochemical system containing steel mesh electrode were evaluated from contaminated water with E. coli, Pseudomonas aeroginosa, Staphylococcus aureous and Streptococcus fecalis at various concentrations. Effect of current density, supporting electrolyte and pathogeni...
متن کاملCORROSION BEHAVIOR OF BIOACTIVATED TITANIUM DENTAL IMPLANT USING DIFFERENT CHEMICAL METHODS
At the past, damaged tissue was removed from the body of patients. But now tissue regeneration using scaffolds and implants are used to repair the damaged tissue and organs. Besides of the mechanical properties of metallic biomaterials, they suffer from bioinertness. Using some surface treatment techniques, the bioactivity and also corrosion resistance of titanium implants could be improved. In...
متن کامل