From Micro to Nano: Correlative 3D Microscopies for Analysis of Biointerfaces
نویسندگان
چکیده
Orthopaedic and dental implant materials rely heavily on their ability to integrate with bone tissue for successful clinical outcomes, where osseointegration refers to the direct bonding between titanium implants and bone [1]. Evaluating osseointegration, particularly at early time points, presents a variety of challenges. In order to correlate the bone growth mechanisms at implant surfaces to macroscale implant biocompatibility various three-dimensional (3D) microscopies have been utilized, including XRay microcomputed tomography (micro-CT), focused ion beam microscopy (FIB) and Z-contrast electron tomography.
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