Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs.
نویسندگان
چکیده
Dual 5-LOX/COX inhibitors are potential new drugs to treat inflammation. They act by blocking the formation of both prostaglandins and leucotrienes but do not affect lipoxin formation. Such combined inhibition avoids some of the disadvantages of selective COX-2 inhibitors and spares the gatrointestinal mucosa.
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 62 6 شماره
صفحات -
تاریخ انتشار 2003