Spermicidal Activity in Vitro of Bark Extract of Azadirachta Indica in Rats

نویسندگان

  • Vinita Bhargava
  • A.O. Prakash
چکیده

Ethanolic extract of bark of Azadirachta indica showed potent spermicidal activity when tested on rat spermatozoa in vitro. When the extract was applied in 1:1 and 1:2 ratio at tree different concentration using wet drop method, cent percent mortality of spermatozoa was observed within 10 seconds. 10% concentration of the extract was considered as an effective dose.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Review on Spermicidal Activities of Azadirachta indica

In recent year, there were various types of contraceptives developed having different mode of action. These contraceptives are prepared from natural as well as synthetic sources. These contraceptives worked by prevent the fusion of sperm into ovum, change female hormonal levels and spermicidal activity. Many compounds with different pharmacological activity have been evaluated in vitro for thei...

متن کامل

Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats

Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001). Sperm motility and density were significantly reduced. Reduced testicular and accessory organ pro...

متن کامل

Spermicidal Activity of Azadirachta indica (Neem) Aqueous Leaf Extract on Male Albino Rats

The effect of aqueous leaf extract of Azadirachta indica (Neem) on reproduction was studied on male albino rats. The study was divided into three groups of six animals each. The first group (I) received distilled water serve as control. The second and third groups (II and III) of animals were administered the aqueous leaf extract daily at 250mg/kg body wt., and 350mg/kg body wt., respectively f...

متن کامل

Strengthening of antioxidant defense by Azadirachta indica in alloxan-diabetic rat tissues

BACKGROUND Azadirachta indica has been reported to correct altered glycaemia in diabetes. OBJECTIVE The aqueous extract of A. indica leaf and bark has been evaluated for its effect on antioxidant status of alloxan diabetic rats and compared with insulin treatment. MATERIALS AND METHODS The oral effective dose of A. indica leaf (500 mg/kg body weight) and A. indica bark (100 mg/kg body weigh...

متن کامل

Anti – Inflammatory and Antimicrobial Activities of the Root, Bark and Leaves of Azadirachta Indica

Azadirachta indica is a plant of varied uses in Ayurveda since ancient times and is highly extolled by expert physicians and as well as practitioners of folk medicines. Almost every part of the tree has long been used in folklore and traditional systems of medicine for the treatment of a variety of human ailments. The 50% acetone extract of the root, bark and leaves of A. indica sowed marked an...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2000