Effective treatment of multifocal aggressive fibromatosis with low-dose chemotherapy.
نویسندگان
چکیده
Desmoid tumor (aggressive fibromatosis), as a member of a group of borderline neoplasms, is a rare tumor of fibroblastic origin that remains difficult to treat. Treatments with surgery, radiotherapy and different medical protocols including interferon (IFN)-alpha, hormonal agents such as tamoxifen (anti-estrogen) as well as non-steroidal anti-inflammatory drugs and low-dose antineoplastic agents have been reported. In this report we describe a new patient with multifocal aggressive fibromatosis who was successfully treated with low-dose chemotherapy consisting of methotrexate and vinblastine.
منابع مشابه
Aggressive Fibromatosis of Parapharyngeal Space: a rare case report
Aggressive fibromatosis also known as extra abdominal desmoid tumor is an uncommon benign tumor of soft tissue origin with fibroblastic proliferationSince the tumor is locally aggressive, the lesion may be misdiagnosed as low -grade fibrosarcoms. It accounts for 0.03% - 0.1% of all body tumors and 3% of all soft tissue tumors. Only 10% to 15% of these lesions occur in head and neck, usually in ...
متن کاملAggressive Fibromatosis of Parapharyngeal Space: a rare case report
Aggressive fibromatosis also known as extra abdominal desmoid tumor is an uncommon benign tumor of soft tissue origin with fibroblastic proliferationSince the tumor is locally aggressive, the lesion may be misdiagnosed as low -grade fibrosarcoms. It accounts for 0.03% - 0.1% of all body tumors and 3% of all soft tissue tumors. Only 10% to 15% of these lesions occur in head and neck, usually ...
متن کاملThe Analysis of Treatment of Aggressive Fibromatosis Using Oral Methotrexate Chemotherapy
BACKGROUND Aggressive fibromatosis is a rare but invasive tumor infiltrating widely between fascia and muscle fibers. It has a high tendency to be locally recurrent despite complete resection. Effectiveness of adjuvant treatment for aggressive fibromatosis including radiotherapy, pharmacological agents, hormonal treatments, and chemotherapy have been previously reported. The purpose of this art...
متن کاملAggressive Fibromatosis, Clinicopathologic Findings of 25 Cases; A Single-Center Experience and Review of the Literature
Background: Aggressive fibromatosis is a rare benign tumor with no potential for metastasis; however, its aggressive nature causes treatment failure and episodes of recurrence. There is no report from Iran about the treatment of this tumor, and all published articles are single-case reports, therefore in this study, we report our experience from two of...
متن کاملFibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine.
Fibromatosis is a rare disease with benign histology. Its infiltrative growth pattern may prevent complete resection. We report a case of a 40-year-old woman with fibromatosis of the neck requiring an emergency operation for acute upper airway obstruction. Gross residual tumour was left behind but excellent tumour shrinkage was achieved by using weekly low-dose methotrexate and vinblastine. Des...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Turkish journal of pediatrics
دوره 48 4 شماره
صفحات -
تاریخ انتشار 2006