Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. II. Physico-chemical properties and structure determination.

نویسندگان

  • A Takahashi
  • H Nakamura
  • T Kameyama
  • S Kurasawa
  • H Naganawa
  • Y Okami
  • T Takeuchi
  • H Umezawa
  • Y Iitaka
چکیده

The structure of bisucaberin, a new siderophore, was determined to be 1,12-dihydroxy-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetron e by spectroscopic analysis and X-ray crystallographic analysis. The molecule of bisucaberin consists of a cyclic dimer of 1-hydroxy-1,6-diazaundecane-2,5-dione moiety and is closely related to nocardamine, the trimer of the same moiety.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 40 12  شماره 

صفحات  -

تاریخ انتشار 1987