Omalizumab and sino-nasal allergy treatment
نویسنده
چکیده
Omalizumab is an anti-human IgE humanized monoclonal antibody produced against CƐ3 domain of the Fc fragment of IgE molecule. Omalizumab suppresses the effector roles of IgE by preventing binding to high-affinity receptors (FcεR1) on allergy-related immune effector cells and blocking mast cell or basophil mediator release.4 Based on this mechanism of action, Omab also provides symptomatic relief to allergic patients.
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