Herpes zoster caused by vaccine-strain varicella zoster virus in an immunocompetent recipient of zoster vaccine.

نویسندگان

  • Hung Fu Tseng
  • D Scott Schmid
  • Rafael Harpaz
  • Philip LaRussa
  • Nancy J Jensen
  • Pierre Rivailler
  • Kay Radford
  • Jennifer Folster
  • Steven J Jacobsen
چکیده

We report the first laboratory-documented case of herpes zoster caused by the attenuated varicella zoster virus (VZV) contained in Zostavax in a 68-year-old immunocompetent adult with strong evidence of prior wild-type VZV infection. The complete genome sequence of the isolate revealed that the strain carried 15 of 42 (36%) recognized varicella vaccine-associated single-nucleotide polymorphisms, including all 5 of the fixed vaccine markers present in nearly all of the strains in the vaccine. The case of herpes zoster was relatively mild and resolved without complications.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 58 8  شماره 

صفحات  -

تاریخ انتشار 2014