Scleromyxedema: a cutaneous paraneoplastic syndrome associated with thymic carcinoma.

Introduction Although it is a rare disorder, scleromyxedema (lichen myxedematosus) is one of the most common forms of primary cutaneous mucinosis. This condition is a generalized form of dermal mucin deposition characterized by waxy papules that progresses to indurated and thickened skin and is often associated with monoclonal gammopathy, particularly of the immunoglobulin G type. Lichen myxedematosus has been rarely reported to be associated with internal malignancies (Table 1). To our knowledge, the coexistence of thymic carcinoma and lichen myxedematosus in the same patient has never previously been documented. In this article, we describe, for the first time of our knowledge, a case of scleromyxedema associated with thymic carcinoma.