Natural Opioid Peptides, Synthetic Analogs, Peptidases: Pharmacological Analysis and Drug
نویسندگان
چکیده
3.1. Chapter 1. Critical overview of the use of isolated organs in opioid research 3.2. Chapter 2. Pharmacological characterisation of enkephalins, ?-endorphin and its fragments 3.3. Chapter 3. Development of potent analgesic enkephalin analogs such as (D-Met2,Pro5)-enkephalinamide 3.4. Chapter 4. Characterisation of structural principles for the receptor type-selectivity of enkephalin analogs 3.5. Chapter 5. Detection of a novel dipeptidyl-carboxypeptidase in rodent blood vessel and human adrenomedullary tumors 3.6. Chapter 6. Design and pharmacological characterisation of novel, pure and highly ?-opioid receptor type-selective and ?-opioid receptor type.selective peptide antagonists: the principle of N-acylation.
منابع مشابه
اپوئیدها(Opioids) و دستگاه گوارش
SUMMARY The term opioid was coined to refer in a generic sense to all drugs, natural and synthetic, with morphin - like actions. Three distinct families of peptides have been identified so far in gastrointestinal (GI) nervous system in mammalian. These peptides include : dynorphin, Met - enkephalin and leu - enkephalin . Results from studies about opioid which have been started 15 years ago ...
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