Antioxidant and antidiabetic activities of extracts from Cirsium japonicum roots
نویسندگان
چکیده
This study investigated the antioxidant activity of methanol (MeOH) and water extracts from roots of Cirsium japonicumin vitro. MeOH extract showed a stronger free radical scavenging activity than water extract. However, both of extracts showed a concentration dependent hydroxyl radical scavenging activity, reducing power and metal chelating ability. MeOH extract had greater phenolic and flavonoid contents than water extract. The antidiabetic activity of these two extracts was evaluated by the alpha-glucosidase inhibition assay. The water extract showed a considerable alpha-glucosidase inhibitory activity. To our knowledge, this may be the first time to report the antioxidant and antidiabetic activities in Cirsium japonicum roots.
منابع مشابه
Antioxidant Activity of Two Flavonol Glycosides from Cirsium Hypoleucum Dc. through Bioassay- Guided Fractionation
The flowers, roots and stems of Cirsium species are used as a folk remedy in Anatolia. In order to evaluate antioxidant activity of Cirsium hypoleucum which is an endemic plant, superoxide radical (hypoxanthine-xanthine oxidase system) and free radical scavenging activities (DPPH) using in vitro electron spin resonance (ESR) spectrometry of the different extracts, fractions and compounds obtain...
متن کاملComparative Analysis of Chemical Profile, Antioxidant, In-vitro and In-vivo Antidiabetic Activities of Juniperus foetidissima Willd. and Juniperus sabina L.
Fruit and leaves of junipers are commonly used internally as tea and pounded fruits are eaten to lower blood glucose levels in Anatolia. Thus, we aimed to evaluate antidiabetic and antioxidant potential and the chemical profile of Juniperus foetidissima Willd. and J. sabina L. in this study. In-vitro antidiabetic activities of leaf and fruit extracts were examined by their inhibitory activity o...
متن کاملComparative Analysis of Chemical Profile, Antioxidant, In-vitro and In-vivo Antidiabetic Activities of Juniperus foetidissima Willd. and Juniperus sabina L.
Fruit and leaves of junipers are commonly used internally as tea and pounded fruits are eaten to lower blood glucose levels in Anatolia. Thus, we aimed to evaluate antidiabetic and antioxidant potential and the chemical profile of Juniperus foetidissima Willd. and J. sabina L. in this study. In-vitro antidiabetic activities of leaf and fruit extracts were examined by their inhibitory activity o...
متن کاملAntidiabetic and Antioxidant Activities of Zizyphus lotus L Aqueous Extracts in Wistar Rats
Objectives: Zizyphus lotus L. is a medicinal plant, used in traditional medicine for its multiple therapeutic properties. The aim of the present study was to determine the antidiabetic and antioxidant effects of aqueous extracts of different parts of Zizyphus lotus in diabetic Wistar rats. Research methods and procedures: The male Wistar rats were rendered diabetic by intraperitoneal (i.p.) inj...
متن کاملAntioxidant and antibacterial activities of the essential oils and extracts of Dorema ammoniacum roots and aerial parts
Background and objectives: Dorema ammoniacum D. Don (Apiaceae) is a monocarpic plant endemic to central Iran. The gum resin of this species is a known therapeutic agent in Iranian, Indian and Western traditional medicines. The aim of the present study was to investigate essential oil constituents and evaluation of antioxidant and antibacterial activities of the essential oils and extra...
متن کامل